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// Powered by Mass Cytometry - Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes

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Rahim et al. show that immune checkpoint blockade activates CD8 T cell differentiation and proliferation in the lymph node, not within the tumor microenvironment, and these cells can be detected in transit via blood profiling.

A distinct stimulatory cDC1 subpopulation amplifies CD8+ T cell responses in tumors for protective anti-cancer immunity - ScienceDirect

Lymph Node Delivery Strategy Enables the Activation of Cytotoxic T Lymphocytes and Natural Killer Cells to Augment Cancer Immunotherapy

Dynamics and specificities of T cells in cancer immunotherapy

Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes - ScienceDirect

Whole-body CD8+ T cell visualization before and during cancer immunotherapy: a phase 1/2 trial

Frontiers The Emerging Interplay Between Recirculating and Tissue-Resident Memory T Cells in Cancer Immunity: Lessons Learned From PD-1/PD-L1 Blockade Therapy and Remaining Gaps

Cytotoxic CD8+ T cells in cancer and cancer immunotherapy

Induction of oligoclonal CD8 T cell responses against pulmonary metastatic cancer by a phospholipid-conjugated TLR7 agonist

Melanoma-derived mediators can foster the premetastatic niche: crossroad to lymphatic metastasis: Trends in Immunology

Cancers, Free Full-Text

Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes - ScienceDirect

Frontiers Targeting the immune microenvironment for ovarian cancer therapy

// Powered by Mass Cytometry - Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes

Targeting tumor extracellular matrix activates the tumor-draining lymph nodes

Targeting the epigenome to reinvigorate T cells for cancer immunotherapy, Military Medical Research